Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

Substrate:

HSP 90-alpha (heat shock protein HSP 90-alpha (HSP 86) (from PhosphoBase))

Seq-ID:

P07900 [Homo sapiens]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

[show]

MINT-13696   SYEP_HUMAN
MINT-17372   SYMC_HUMAN
MINT-17385   SYQ_HUMAN
MINT-48053   IKKA_HUMAN
MINT-48091   IKKB_HUMAN
MINT-48120   IKKE_HUMAN
MINT-48190   NEMO_HUMAN
MINT-48342   M3K1_HUMAN
MINT-48497   M3K3_HUMAN
MINT-48682   NFKB1_HUMAN
MINT-48760   NFKB2_HUMAN
MINT-48857   M3K14_HUMAN
MINT-49053   RIPK1_HUMAN
MINT-49073   RIPK2_HUMAN
MINT-49177   TAB1_HUMAN
MINT-49213   TAB2_HUMAN
MINT-49282   TBK1_HUMAN
MINT-63931   RS3A_HUMAN
MINT-3305183   1433Z_HUMAN
MINT-3373863   LCK_HUMAN
MINT-3374106   ZAP70_HUMAN
MINT-3378991   FKBP8_HUMAN
MINT-6550966   HIF1A_HUMAN
MINT-7710224   FKBP4_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, TPR domain binding, unfolded protein binding, nitric-oxide synthase regulator activity, ATP binding	cytosol, melanosome	mitochondrial outer membrane translocase complex assembly, response to unfolded protein, positive regulation of nitric oxide biosynthetic process, mitochondrial transport, signal transduction, protein refolding, cellular chaperone-mediated protein complex assembly

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	5	MPEETQTQDQPMEEE	-	2507541	LTP	0.08		-	-	0.97	-	-
T	7	MPEETQTQDQPMEEEEV	DNA-PK	2507541	LTP	0.25	MOD_PIKK_1	-	-	0.95	-	-
T	7	MPEETQTQDQPMEEEEV	DNA-PK	2507541	LTP	0.25	MOD_PIKK_1	-	-	0.95	-	-
S	231	FVEKERDKEVSDDEAEEKEDK	-	15822905	HTP	0.81	MOD_CK2_1	-	COIL	0.70	-	-
S	231	FVEKERDKEVSDDEAEEKEDK	CK2_group	2492519	LTP	0.81	MOD_CK2_1	-	COIL	0.70	-	-
S	231	FVEKERDKEVSDDEAEEKEDK	-	17081983	HTP	0.81	MOD_CK2_1	-	COIL	0.70	-	-
S	231	FVEKERDKEVSDDEAEEKEDK	-	18088087	HTP	0.81	MOD_CK2_1	-	COIL	0.70	-	-
S	231	FVEKERDKEVSDDEAEEKEDK	-	17287340	HTP	0.81	MOD_CK2_1	-	COIL	0.70	-	-
S	252	EEEKEKEEKESEDKPEIEDVG	-	17081983	HTP	0.04		-	COIL	0.81	-	-
S	252	EEEKEKEEKESEDKPEIEDVG	-	18088087	HTP	0.04		-	COIL	0.81	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	-	15822905	HTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	CK2_group	2492519	LTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	CK2_alpha	2492519	LTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	CK2_group	2492519	LTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	CK2_alpha	2492519	LTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	-	17081983	HTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	-	18088087	HTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	-	17287340	HTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
S	263	EDKPEIEDVGSDEEEEKKDGD	-	18669648	HTP	0.10	MOD_CK2_1	-	HSP90	0.78	-	-
T	725	EMPPLEGDDDTSRMEEVD	-	18669648	HTP	0.05		-	HSP90	0.88	-	-
S	726	MPPLEGDDDTSRMEEVD	-	18669648	HTP	0.65		-	HSP90	0.88	-	-

Substrate:

HSP 90-alpha (heat shock protein HSP 90-alpha (HSP 86) (from PhosphoBase))

Seq-ID:

P07901 [Mus musculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

MINT-6978911 AKT1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, TPR domain binding, unfolded protein binding, nitric-oxide synthase regulator activity, ATP binding	cytosol, melanosome	response to unfolded protein, positive regulation of nitric oxide biosynthetic process, protein refolding, nitric oxide biosynthetic process, positive regulation of cytotoxic T cell differentiation

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	5	MPEETQTQDQPMEEE	-	2507541	LTP	0.08	-	-	0.97	-	-
T	7	MPEETQTQDQPMEEEEV	-	2507541	LTP	0.15	-	-	0.95	-	-
S	263	DDKPEIEDVGSDEEEEEKKDG	-	17203969	HTP	0.11	-	HSP90	0.80	-	-
S	263	DDKPEIEDVGSDEEEEEKKDG	-	19144319	HTP	0.11	-	HSP90	0.80	-	-

Substrate:

HSP 90-alpha (heat shock protein HSP 90-alpha (HSP 86) (from PhosphoBase))

Seq-ID:

P30946 [Oryctolagus cuniculus]

Download:

fasta csv

Interaction Network(s):

External Source(s):

MINT Interaction(s):

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
unfolded protein binding, ATP binding	melanosome	protein folding, response to stress

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
T	4	PEETQTQDQPMEEE	-	2507541	LTP	-		-	-	0.99	-	-
T	6	PEETQTQDQPMEEEEV	-	2507541	LTP	-		-	-	0.98	-	-